Objective To estimate the reliability of the hallucination symptom via quantum resonance spectrometer (QRS). Methods The hallucination symptom that psychiatrists diagnosed were compared with the test results via quantum resonance spectrometer. Results Using quantum resonance spectrometer to detect the auditory hallucination symptom has good sensitivity ( 97.6% ) and accuracy ( 89.0% ) ( x2 = 19.42, P < 0.01 ). There was no statistically significant of the visual hallucination ( x2 = 0.89, P > 0.05 ) and the taste hallucination ( x2 =0. 53, P > 0.05 ). And the hallucination of visceral sensation was also not with statistical significance ( x2 = 0.22,P > 0. 05 ). Conclusion Using quantum resonance spectrometer will provide a new basis for the early detection and diagnosis of the auditory hallucination,which may be important for accessorial diagnosis of schizophrenia.