Polymer solar cells (PSCs) are considered as the most promising third-generation photovoltaic technology in the future due to their advantages such as light weight, thin film and flexibility. Nowadays, the power conversion efficiencies (PCE) of PSCs have pasted 13％, laying the foundation for their fab-scale production. To realize the scalable fabrication of PSCs, the key issue is developing high efficiency thick film PSCs compatibility to the roll-to-roll (R2 R) printing process. In this article, different kinds of high efficiency thick film PSCs including fullerene PSCs, nonfullerene PSCs and ternary PSCs are reviewed according to the recent research progress. The relevant research works on the molecular design of donor and acceptor materials, morphology of photoactive layers, fabrication method and mechanism of solar cells devices are discussed. And the future prospect of the research on thick film PSCs is presented.