Related to future planning and development of the enterprise,business location and layout is the most important part in the man-agement strategy. Due to the limitations of the traditional research methods,business sites are crying for the new technologies in order to adapt to the fundamental shift of modern business models. In order to reduce the cost of enterprises,obtain more market share and offer better service for the customers,analyze three key impacts of the commercial net location,that is to say,population,transportation and market competition. Business Analyst Online ( BAO) is introduced with its main process of business location and examples. The best bus-iness location is acquired in the conclusion,which provides a reference for decision makers to make business objectives and strategy.