Objective To investigate the effects of radiotherapy after radical resection of gallbladder carcinoma. Methods Forty-seven patients with Navin Stage Ⅱand Ⅲgallbladder carcinoma admitted to He’nan Cancer Hospital Affiliated to Zhengzhou University from Jan. 2011 to Jan. 2016 were assigned to the group including 28 patients not re-ceiving postoperative adjuvant therapy ( NT group) , or the group receiving postoperative adjuvant radiotherapy ( RT group) ; overall survival and disease-free survival were compared between two groups. Results There was statistically significant difference in postoperative disease-free survival between two groups ( P=0. 014) ; while there was no statisti-cally significant difference in postoperative overall survival between two groups ( P=0. 118) , the median survival was longer in the RT group (18. 4 months) than that in the NT group (13. 8 months). Conclusion Adjuvant radiotherapy after radical resection has positive effects on the long-term prognosis of patients with StageⅡandⅢgallbladder carcinoma.