In order to solve the erosive wear problems in the impeller in the high water-cut stage, the RNG k-εturbulence model, discrete phase model and SIMPLEC algorithm are employed to realize the simulation of an electric submersible pump's ( ESP) erosive wear. The effects of the working condition and structural parameters of the ESP are also studied. The results show that the concave side of the impeller's blade is a serious eroded area. With the increases of the sand volume fraction and the impeller speed, the impeller's wear rate goes up. With the increase of the particle size and outlet angle, the wear rate firstly rises then reduces. Finaly, the impeller's average wear rate reduces with the increase of the inlet angle.