Objective:To explore the new liquid infrared irradiation combined local oxygen therapy and rehabili-tation treatment of senile diabetes clinical curative effect of pressure ulcers. Methods:86 patients with pressure ul-cers were divided into observation group and control group, 43 cases each. The control group were treated by conven-tional method applying pressure ulcers, observation group application infrared irradiation combined local new liquid oxygen therapy and rehabilitation treatment of pressure ulcers. Observation compared two groups of patients with pressure ulcers wound healing. Results:The infrared irradiation combined local new liquid oxygen therapy and reha-bilitation treatment of senile diabetes pressure ulcer clinical effect is remarkable, compared with the conventional method to shorten the ulcer healing time, differences were statistically significant (P<0.05). Conclusion:Using in-frared irradiation combined local new liquid oxygen therapy and rehabilitation treatment of senile diabetes pressure ulcers, can improve local tissue ischemia and hypoxia pressure ulcers, short cure time, safe and effective.