[Objective]To study the biodiversity of mammals and birds in the Qingliangfeng National Nature Reserve,Anhui Province.[Method] From December of 2015 to March of 2016 ,the biodiversity of mammals and birds in the Qingliangfeng National Nature Reserve were investigated by using camera infrared technology.[Result]15 species,11 families,6 orders(including 9 mammal species and 6 bird species) were identified. Among them,Syrmaticus ellioti and Muntiacus crinifrons were ClassⅠstate key protected wild animals,and Lophura nythemera,Pucrasia macrolopha and Capricornis milneedwardsii were ClassⅡstate key protected wild animals.Based on the relative abundance index,Niviventer confucianus, Lepus sinensis and Muntiacus reevesi were ranked as the 3 most abundant mammal species ,while L.nythemera,Parus major and P.macrolopha were ranked as the three most abundant bird species.The number of recorded species by camera traps in core area was significantly more than that in buffer area.[Conclusion]The study could provide scientific basis for long-term monitoring and conservation of wild animals further.